I've got about 50 users, I do about 2GB monthly in traffic. I host about 13 small business sites, using SSL and HTTP traffic. Of those 50 users, about 40 use it as their primary mail server. I'm also doing pop-before-smtp services.
Load averages are about 0.03, 0.04, 0.15
Doing RAID-1 on two 5400 1.2GB drives, disk I/O is fast.
Memory is 256 MB, consumed is about 60MB.
Processor is a Celeron 333
Using PHP Accelerator (freeware ZEND) and mod_gzip to increase speed for http/php traffic.
Running a very updated version of a 4.1.2 (Apache 1.3.27, current MYSQL, all RH errata bug-fixes applied, etc).